This implementation guide aims to assist those interventions working on HIV combination prevention and chemsex in improving the quality of their project work

Phenomena such as the use of any combination of drugs such as crystal methamphetamine, mephedrone and/or other party drugs before or during sex (chemsex), need to be addressed quickly and adequately. In relationships where any partner is engaged in high‐risk behaviour such as injecting drug use, innovative HIV prevention interventions should address the risk of sexual transmission. Work on sexual and reproductive health and rights (SRHR), while including reproductive health, needs to be inclusive of all SRHR issues and identities, especially now as sexual and reproductive health and rights (SRHR) are at stake where developments in a number of countries reduce SRHR to reproductive health only.

Civil society and community based organisations have a crucial role to play in identifying and responding to emerging health risks and challenges, and in accessing key populations.